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Van Allen is CEO of TimeLine Recruiting. Allen has built his firm into a national, influential force in the medical recruiting industry. To compare the cost of several common modalities used to treat non-genital warts in immunocompetent patients, we identified studies published in English using standard search strategies and evaluated the literature for the following common non-genital wart therapies: cryotherapy with liquid nitrogen, carbon dioxide and pulsed-dye laser therapy, topical squaric acid, intralesional bleomycin, intralesional interferon alpha injections, and intralesional immunotherapy with Candidu antigens. Standard treatment algorithms, compiled by dermatologists experienced in the treatment of patients with moderate wart burdens, were utilized for cost-comparison analyses.

The function of a usual source of care has been extensively discussed in the health services, public health, and medical literature. Age, gender, race, ethnicity, income, education, insurance status, and health status were found to be common correlates of having a regular source of care (Hayward et al. 1991; Hayward et al. 1988; Merzel 2000; Newacheck, Pearl et al. 1998; Newacheck, Stoddard et al. 1998; Rask et al. 1994; Schur, Albers, and Berk 1995; Shi 1999; Weinick and Drilea 1998; Zuvekas and Weinick 1999). Having a usual source of care was demonstrated to be positively correlated with an individual''s general access to the health care system (Weissman et al. 1991), improvement of patients'' satisfaction with medical care (Hurley, Gage, and Freund 1991), a decrease in the use of the emergency department (Newschaffer et al. 1999), a reduction in the likelihood of hospital admission (Weiss and Blustein 1996), and promotion of proper use of medication (Smith and Kirking 1999).

Because of their arguably extreme nature, and the fact that regulatory agencies did eventually intervene, these cases could all too easily be brushed aside as the exceptional dirty laundry in an otherwise clean research environment. The rather limited analysis and discussion of finder''s fees in the literature (6) may both reflect and reinforce the unwarranted belief that finder''s fees are rare and adequately dealt with under existing professional and research ethics codes and policies. Offers of finder''s fees ranging between $2,000 and $5,000 per subject are now regarded as "common" in the United States. (7) The lack of similar reports in other countries could give the impression that finder''s fees raise troubling issues only in the United States. This is not the case. We have heard personal testimony from various sources in Canada indicating that many Canadian physicians and other health-care workers receive up to several thousands of dollars for enrolling patients in, or referring them to, clinical trials. Direct evidence of this practice is unfortunately hard to obtain. Those involved have no interest in drawing attention to their activities, and their colleagues are understandably reluctant to speak out.

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